Darna Zaroori Hai is about six stories and a main story that binds them.

Story 1 Actor: Manoj Pahwa. Director: Sajid Khan.Pahwa is a film buff. He watches every new release in the night show on the first day itself. Just as he readies himself to visit a nearby theatre to catch the new release DARNA MANA HAI, his mother cautions him against taking the route via the graveyard. Pahwa dismisses his mother's plea since he doesn't believe in ghosts. On his way back, he dies of cardiac failure outside the graveyard.

Story 2Actors: Amitabh Bachchan, Ritesh Deshmukh. Director: Ramgopal Varma. An aged professor [Bachchan] believes there's someone in his house. At times, the 'invisible person' rushes to the kitchen. Sometimes, he makes himself comfortable on the chair. Is the professor hallucinating? The professor tries to explain the situation to his student [Ritesh], who revolts and in fact advices him to seek psychiatric help. The 'invisible man' finally appears in the mirror.

Story 3Actors: Arjun Rampal, Bipasha Basu, Makrand Deshpande. Director: Prawal Raman.One fateful night, a stranger [Arjun] knocks on the doors of a secluded bungalow. His car has had a breakdown, he needs a mechanic, he ought to make a phone call. The couple [Bipasha, Makrand] living in this house is eccentric. Both constantly try to scare Arjun. When Arjun states that he doesn't believe in ghosts and spirits, Makrand decides to call the spirits. There's a knock on the door and the spirit refuses to go back.

Story 4Actors: Suniel Shetty, Sonali Kulkarni, Rajpal Yadav. Director: Vivek Shah.A Maharashtrian couple [Suniel, Sonali] have an unexpected visitor in the form of a weird salesman [Rajpal Yadav]. He claims to be an insurance agent, but in actuality he's a thief who wants to rob the couple. In the melee that follows, Rajpal pulls the trigger of the pistol and bang!

Story 5Actors: Anil Kapoor, Mallika Sherawat. Director: Jijy Philip.A leading film-maker [Anil] wants to change lanes. After making a couple of family dramas, he is keen to make a horror film next. He decides to write the concluding portions of his script at his bungalow in Khandala. En route, he spots a lone lady [Mallika] and offers to give her a lift till Khandala. When they reach the film-maker's bungalow, the lady tells him that she's a ghost who had died on the Mumbai-Pune highway.

Story 6Actors: Randeep Hooda, Zakir Hussain, Rasika Joshi. Director: Chekeravarthy. On a rainy night, a young man [Randeep] accidentally bumps into a woman. He is petrified. The next morning, when he opens his eyes, he finds himself in the police lock-up. He is accused of murdering a man. He claims he's innocent. The cop [Zakir] refuses to buy the story. The mother of the victim [Rasika] arrives at the police station. And skeletons tumble out of the cupboard.

Story 7The old lady and five children. Director: Manish Gupta.Five kids take shelter in a dilapidated bungalow. There's an old woman in the house. She starts narrating stories. Slowly, the kids die of shock one after the other.